IN THE NEWS

Selected publication:

  • 1-Mirzaei R*, McNeil R, D’Mello C, Sarkar S, Wong B, Visser F, Poon C, Bose P, Yong VW*. Spatially resolved single-cell analysis uncovers protein kinase C-expressing microglia with anti-tumor activity in glioblastoma. *Corresponding author https://www.biorxiv.org/content/10.1101/2023.12.04.570023v2
  • 2-Mirzaei R, D’Mello C, Nikolic A, Kumar M, Liu M, Sarkar S, Bose P, Gallo M, Yong VW. Single cell spatial analysis identifies regulators of brain tumor initiating cells. Cancer Research. 2023 May 15;83(10):1725-1741.
  • 3-Mirzaei R, Yong VW. Microglia – T cell conversations in brain cancer progression. In press. Trends Mol Med. 2022 Sep 5;S1471-4914(22)00211-8.
  • 4-Mirzaei R, Gordon A, Zemp F, Kumar M, Sarkar S, Luchman H, Bellail A, Hao C, Mahoney D, Dunn J, Bose P, Yong VW. PD-1 independent of PD-L1 ligation promotes glioblastoma growth through the NFB pathway. Science Advances. 2021 Nov 5;7(45):eabh2148.
  • 5-Dzikowski L*, Mirzaei R*, Sarkar S, Kumar M, Bose P, Bellail A, Hao C, Yong VW. Fibrinogen in the glioblastoma microenvironment contributes to the invasiveness of brain tumor-initiating cells. Brain Pathol. 2021 Sep;31(5):e12947. *Co-first author.
  • 6-Mirzaei R, Sarkar S, Dzikowski L, Rawji KS, Khan L, Faissner A, Bose P, Yong VW. Brain tumor-initiating cells export tenascin-C associated with exosomes to suppress T cell activity. OncoImmunology. 2018 Aug 6;7(10):e1478647.
  • 7-Sarkar S, Yang R*, Mirzaei R*, Rawji K, Poon C, Mishra MK, Zemp FJ, Bose P, Kelly J, Dunn JF, Yong VW. Control of brain tumor growth by reactivating myeloid cells with niacin. Sci Transl Med. 2020 Apr 1;12(537):eaay9924. *Co-second author.
  • 8-Kaushik DK, Bhattacharya A, Mirzaei R, Rawji KS, Ahn Y, Rho JM, Yong VW. Enhanced glycolytic metabolism supports transmigration of brain-infiltrating macrophages in multiple sclerosis. J Clin Invest. 2019 May 21;129(8):3277-3292.
  • 9-Sarkar S, Mirzaei R, Zemp FJ, Wei W, Senger DL, Robbins SM, Yong VW. Activation of NOTCH Signaling by Tenascin-C Promotes Growth of Human Brain Tumor-Initiating Cells. Cancer Res. 2017 Jun 15;77(12):3231-3243.
  • 10-Mirzaei R, Sarkar S, Yong VW. T Cell Exhaustion in Glioblastoma: Intricacies of Immune Checkpoints. Trends Immunol. 2017 Feb;38(2):104-115.